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Filling and closing machine for ampoules and injection bottles

07 June 2016

Bosch Packaging Technology presented the latest generation of the ALF series at Pharmatag 2016 on May 10 and 11 in Crailsheim, Germany.

In addition to many detail improvements, the new filling and closing machine offers an increased output of up to 600 ampoules per minute. “Not only regarding its output, the new ALF 5000 is situated in the high-performance range,” Tobias Göttler, product manager at Bosch Packaging Technology, emphasises.

Optimised design, high process safety

The improved pharmaceutical design of the new ALF 5000 is clearly visible: the machine table top is conceived without steps and interfering edges, providing a better sealing from the sterile area. Moreover, the machine’s improved accessibility ensures easy and reliable cleaning. In addition to the common right-hand version, the ALF 5000 is now also available as left-hand version, which enables optimal adaption to existing production sites and workflows such as internal itineraries.

“During the development process, we put special emphasis on even higher process safety,“ says Göttler. “For instance, the ampoule heads are removed sidewards during closing instead of from above.” This avoids machine movements above the open ampoules, making the process safer and more reliable. For a particularly gentle processing, it is now possible to use a carrying rake transport system that slightly lifts the glass containers to prevent them from rubbing against the machine guide. 

Maximum flexibility

Whether four, six, eight, ten or twelve filling points – all established filling systems such as peristaltic pump or time-pressure-filling system can be used with the new machine. In its combi version, the ALF 5000 optionally processes injection bottles in addition to ampoules, which further increases production flexibility for drug manufacturers and contract packers, combined with easy changeovers. As an option, customers can also choose between a statistical or a 100 percent in-process control, as well as different infeed and outfeed versions.

“We have used our expertise from more than 2,000 delivered filling and closing machines for ampoules and combined it with our successful technology from other machine series,” Göttler explains. “The result is an especially flexible solution that can be tailored to specific customer requirements.” Due to its compact design, the ALF 5000 is suited for wall mounting and integration into barrier systems without difficulty. Following Bosch’s pharmaceutical line competence approach, the new filling and closing machine can be combined with upstream and downstream equipment to form a complete line.


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